Testosterone Deficiency

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Causes

Testosterone deficiency (hypogonadism) may be present at birth (congenital) or may develop later (acquired).
It is classified by the location of its cause along the hypothalamic-pituitary-gonadal axis:

Primary, disruption in the testicles
Secondary, disruption in the pituitary
Tertiary, disruption in the hypothalamus


The most common congenital cause is Klinefelter's syndrome. This condition, which is caused by an extra X chromosome, results in infertility, sparse facial an...Read the full article